The use of GPS technologies and geo-mapping software to optimize delivery routes has made logistics more precise, and in turn, more efficient. Transforming information management platforms—from medical supplies inventory management to online ordering—has been critical to more efficient processes. Innovations in warehouse construction have allowed storage units to be located closer to health facilities. In this report we recount the gradual process of reform and improvement in Tanzania, highlighting the extraordinary efforts of local policymakers and program implementers, as well as their collaborations with international organizations and private-sector partners.